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… is from page 152 of Randy Holcombe’s excellent 1995 book, Public Policy and the Quality of Life [2]:
If drugs were legalized, there would not be the same incentives to produce drugs in concentrated doses. Transportation is more costly for illegal drugs because they must be concealed from law enforcement officers. Drugs that can contain more doses in a given volume will be more valuable, and one of the motivations of designer drugs is to allow easier transportation through more concentrated doses. Using alcohol as an example, high-proof liquor was more often produced than beer with low alcohol content during prohibition. Legalization would result in drugs that are not as strong.